Mills

Omni Bead Ruptor 12 Bead Mill Homogenizer

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Omni Bead Ruptor 24 Elite Bead Mill Homogenizer

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Omni Bead Ruptor 4 Bead Mill Homogenizer

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Omni Bead Ruptor 96 Well Plate Homogenizer

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Bead Mills: Efficient and Powerful Sample Disruption in the Laboratory

Bead Mills (or Bead Beaters) are essential tools in modern laboratories, especially in life sciences and molecular biology. These instruments are designed for the rapid and efficient mechanical disruption of a wide range of biological samples, from cells and soft tissues to extremely tough samples like plants, seeds, bones, or resistant microorganisms, enabling optimal extraction of DNA, RNA, and proteins.

Operating Principle: High-Speed Grinding with Beads

The grinding technology in bead mills is based on the rapid and forceful movement (often three-dimensional) of tubes containing the sample, extraction buffer, and small grinding beads. The beads, made of various materials (glass, ceramic, metal) and sizes, collide with the sample and the tube walls at high speed, causing mechanical breakage and efficient disruption of cellular and tissue structures (Lysis). The process takes place in a closed system (disposable tubes), preventing cross-contamination between samples and protecting the user.

The choice of bead type and quantity, as well as grinding intensity and duration, can be adjusted according to the sample type and extraction target, allowing for protocol optimization to achieve the best results.

Key Applications in Molecular Biology and Genomics Research

Bead mills are essential for a wide variety of applications requiring efficient sample disruption:

• Nucleic Acid Extraction: Genomic DNA, plasmids, total RNA, miRNA from diverse samples (blood, tissues, cultured cells, feces, soil, plants, bacteria, yeast, fungi, etc.).
• Protein Extraction: Isolation of active proteins or for analysis (Western Blot, Mass Spectrometry).
• Tissue Homogenization: Preparing uniform samples for biochemical or histological analysis.
• Microorganism Disruption: Breaking tough cell walls of bacteria, yeast, algae, or spores.
• Environmental Studies: Extracting metagenomic DNA from soil or water samples.
• Agricultural Research: Extracting genetic material from plants, seeds, or plant pathogens.

Advanced Grinding Solutions from the Omni Bead Ruptor Series at Labotal

Labotal is proud to offer the advanced Bead Ruptor series of bead mills from the American company Omni International, a leader in developing innovative sample preparation solutions. The Bead Ruptor series includes a range of models suited to different throughput needs: from the compact Bead Ruptor 4 for processing up to 4 samples, through the popular Bead Ruptor 12 and Bead Ruptor 24 Elite for medium throughput, up to the Bead Ruptor 96 designed for high-throughput processing of entire plates.

Bead Ruptor mills excel in disruption speed and efficiency, reliability, and their ability to deliver consistent, reproducible results. They offer great flexibility in protocol selection and are suitable for an extremely wide range of sample types and tubes. Choosing Omni through Labotal ensures not only high-quality instrumentation but also professional guidance and advice in selecting the appropriate model, bead types, and optimal protocols for your applications, along with excellent service and technical support.

Looking for an efficient, fast, and reliable way to disrupt your samples? Discover the Omni Bead Ruptor series of bead mills. Contact Labotal’s experts for personalized advice, matching the best solution for your lab, and a quote. Click here to contact us and get advice.