Vacuum Concentration

Labconco Refrigerated Vacuum Concentrator - CentriVap Pro

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Centrivap Bench-Top Vacuum Concentrator, Labconco

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Centrivap Refrigerated Bench-Top Vacuum Concentrator, Labconco

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Rapidvap Vacuum Evaporator, Labconco

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Vacuum Drying: Efficient Concentration and Evaporation of Samples

The Vacuum Drying category includes advanced laboratory equipment designed for the rapid and efficient evaporation of solvents from liquid samples, utilizing controlled vacuum conditions, sometimes combined with heat and/or centrifugation. These methods are essential for concentrating biological samples, removing solvents after separation or extraction processes, and preparing samples for analysis, all while preserving sample integrity.

Operating Principles: Vacuum, Heat, and Centrifugation/Vortexing

Vacuum drying systems work by lowering the pressure in the sample chamber using a vacuum pump. This lowers the boiling point of solvents, allowing for rapid evaporation at relatively low temperatures. Different techniques are used to accelerate the process and prevent undesirable phenomena:

• Vacuum Concentrators: These devices, like the Centrivap series, combine vacuum, heat (often optional or controlled), and centrifugation. The rapid rotation of the rotor creates a concentration gradient in the tube and prevents “bumping” of the sample during boiling, while efficiently concentrating the remaining solid or liquid at the bottom of the tube. Refrigerated models offer protection for particularly heat-sensitive samples.
• Vacuum Evaporation Systems: These systems, like the Rapidvap series, use a combination of vacuum, controlled heating, and vortex motion of the samples. The vortexing increases the surface area of the liquid and significantly accelerates the evaporation rate, allowing for rapid processing of multiple samples simultaneously.

Key Applications of Vacuum Drying

Vacuum drying and concentration systems are widely used in various laboratory fields:

• Molecular Biology: Concentration of DNA, RNA, oligonucleotides, and peptides.
• Analytical and Clinical Chemistry: Sample preparation prior to analysis (LC-MS, GC-MS), solvent removal after extraction (SPE) or chromatographic separation (HPLC).
• Drug Development and Biomarker Discovery: Concentration of fractions, preparation of combinatorial library samples.
• Proteomics and Genomics: Concentration of protein or nucleic acid samples.
• Environmental Testing: Concentration of pollutants before analysis.

Advanced Concentration & Evaporation Solutions from Labconco and Labotal

Labotal is proud to offer a range of vacuum drying and concentration systems from the American company Labconco, a leading and respected manufacturer of quality laboratory equipment. Labconco’s solutions include:

• Centrivap® Vacuum Concentrators: Reliable and efficient benchtop systems for gentle sample concentration, available in various configurations, including refrigerated models to protect heat-sensitive samples.
• RapidVap® Evaporation Systems: Fast solutions for evaporating solvents from multiple samples simultaneously, using controlled vortexing, heat, and vacuum.

These systems are known for their reliability, efficiency, and ease of operation. Labotal’s expert team is ready to assist you in selecting the system best suited to your specific needs, considering the type and volume of samples, solvent types, and required throughput. We provide consultation on selecting the complete system, including the appropriate vacuum pump (usually not included), application support, and professional maintenance services.

Streamline your sample concentration and evaporation processes. We invite you to browse the range of vacuum drying systems from Labconco. For more details, professional advice, or a price quote, contact Labotal’s analytical equipment experts.