Pilot Plants

---

Pilot Plant Homogenizers: Bridging Research and Larger-Scale Production

Homogenizers designed for pilot plants represent a critical stage in the development process, bridging the gap between small-scale laboratory experiments and full industrial production. This equipment is engineered to process larger volumes than standard laboratory homogenizers, providing essential data for process optimization (scale-up) and formulation validation before transitioning to mass production.

Operating Principles: Powerful and Reliable Homogenization for Larger Volumes

Pilot-scale homogenizers, like those from Kinematica, often continue to rely on proven rotor-stator technology but are designed for greater power and durability. They are equipped with stronger motors, more massive dispersing aggregates, and a reinforced structure capable of handling volumes ranging from several liters up to tens of liters. The goal is to achieve homogenization results (disruption, emulsion, or dispersion) similar to those obtained in the lab, but on a larger scale, consistently and reliably.

These systems allow for the examination of critical scale-up parameters, such as the effects of increased volume, flow rate, processing time, and aggregate geometry adjustments, while maintaining final product quality.

Key Applications in Scale-Up and Initial Production

Pilot plant homogenizers are essential in various industries and processes:

• Pharma & Biotechnology: Development and production of pilot batches of drugs, vaccines, creams, and emulsions; optimizing cell disruption processes for recombinant protein production.
• Food Industry: Development and initial production of sauces, beverages, spreads, and dairy products; testing formulation stability in larger volumes.
• Cosmetics: Production of pilot batches of creams, lotions, and personal care products for market testing and validation.
• Chemicals & Materials: Developing manufacturing processes for inks, paints, coatings, and polymer dispersions; assessing feasibility for industrial production.
• Research & Development: Creating larger quantities of materials for advanced experiments or initial clinical trials.

Advanced Pilot Plant Homogenization Solutions from Kinematica at Labotal

Labotal is proud to offer advanced homogenization solutions for pilot plants from the Swiss company Kinematica, the global expert in the field. Powerful models from the Polytron series, such as the PT-6100D, are specifically designed to tackle the challenges of scale-up and processing medium-to-large volumes. These instruments deliver the power, reliability, flexibility, and reproducibility required when moving from the lab to production, ensuring a smooth and efficient development process.

Selecting the right pilot-scale homogenization system requires a deep understanding of the process and scale-up challenges. Labotal’s expert team, with extensive experience in Kinematica solutions and industrial applications, will assist you in choosing the most suitable model and configuration for your needs, providing professional guidance from specification to installation, training, and ongoing support.

Planning to move from the lab to the pilot stage? Discover Kinematica’s homogenization solutions designed for larger scales, such as the PT-6100D model. Contact Labotal’s experts today for professional advice on scale-up and selecting a pilot plant homogenization solution. Click here to contact us and get advice.